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Self-drive road trip · Italy

Fly-Drive Rome to Venice

Rome · Siena · Florence · Venice

  • Duration10 Days / 9 Nights
  • Stops4 Cities
  • Start and finishRome – Venice
  • IncludedHotels + car

Per person, estimatedUS$1,988

OverviewDay by dayCarWhat's includedQuestions

About this road trip

Discover Italy at a relaxed pace on this self-drive journey from Rome to Venice. Explore the Eternal City, medieval Siena and Renaissance Florence before returning your rental car at Venice Marco Polo Airport. From there, travel by boat to your Venice hotel and enjoy the lagoon city car-free before your return boat transfer to the airport.

Perfect for

  • Fly-Drive Trips
  • Couples
  • Road Trippers
  • History Buffs
  • Art & Culture Lovers
  • Food & Wine Lovers
  • Photographers
  • First-Time Italy

Why we love this route

  • Rome’s ancient landmarks and lively neighborhoods
  • Scenic drives through Tuscany
  • Medieval Siena and Renaissance Florence
  • Car-free stay in Venice
  • Round-trip boat transfers between Venice Airport and your hotel
  • Hotels you choose
  • Rental car included
  • 24/7 assistance
  • Experts on call

Your trip

Estimated trip price

US$1,988per person

US$3,976total for 2 travelers

  • Includes: 9 hotel nights + 9-day rental car
  • Based on 2 travelers sharing 1 room and 1 car
  • Flight priced separately once you pick one

Would you like to add round-trip flights from your home airport, into Rome and home from Venice?

Travel date

Travelers

Live hotel, car & flight prices on the next step.

TPEarn up to 7,500 TPoints (worth $75) on this booking, redeem for flights, hotels, cars and more. Free to join; sign in to start collecting.

Plan your adventure:Talk to a travel expert

Why You'll Love This Trip

  • Four iconic Italian cities, one seamless route

  • Rental car gives you the freedom to explore at your own pace

  • Centrally located hotels — you walk out the door into the action

  • Longer stays in each city — no rushing from place to place

  • Scenic Tuscan countryside between Siena and Florence

  • Mix of charming 3 and 4-star hotels throughout

  • Easy side trips to Chianti, San Gimignano, Murano, and Burano

Your 10 days at a glance

Your road trip, day by day

Every stop has a hotel already chosen for you. Open a stop to swap the hotel, add activities or stay longer. The price updates as you go.

Want more time somewhere? Open any stop and tap Add a night. Every day after it moves back, and your dates and price update automatically.

10 Days

Make this trip yours

Stay longer or shorter in Rome

Your stay in RomeDays 1–3

2 Nights10 days total

Each night you add pushes the rest of the trip back by a day. Your dates, hotels, car and price all update for you, and you can undo it anytime.

  1. 1
    Arrival

    Rome

    Rome 1
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    1 / 4

    Pick up your car at FIUMICINO (FCO). It's yours for all 10 days.

    Arrive at Rome Fiumicino Airport, collect your rental car and drive to your hotel. During your stay, explore the Colosseum, Roman Forum, Trevi Fountain, Spanish Steps and Vatican City. Allow time for leisurely meals and evening walks through Rome’s historic neighborhoods.

    Overnight: Luxury on the River, night 1 of 2

Your hotel in Rome

10 hotels to choose from
Luxury on the River 1
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Luxury on the River
9.2Exceptional

“Luxury on the River offers an unbeatable riverside location in Rome within walking distance to Vatican and major attractions, paired with spacious, comfortable rooms and exceptionally warm, attentive staff who go above and beyond to ensure guests feel welcomed and cared for throughout their stay.”

Included in your trip2 Nights, Lungotevere Mellini, 34, Rome

Your free time

No set plans here. Wander, linger over dinner and let Rome surprise you.

Make this trip yours

Stay longer or shorter in Siena

Your stay in SienaDays 3–5

2 Nights10 days total

Each night you add pushes the rest of the trip back by a day. Your dates, hotels, car and price all update for you, and you can undo it anytime.

  1. 3
    Drive day

    Siena

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    Leave Rome and drive north into Tuscany. Discover Siena’s UNESCO-listed historic center, Piazza del Campo and medieval streets. With your own car, you can also explore the Tuscan countryside, including San Gimignano or the Chianti wine villages.

    Overnight: Hotel Athena, night 1 of 2

Your hotel in Siena

9 hotels to choose from
Hotel Athena 1
Hotel Athena 2
Hotel Athena 3
Hotel Athena 4
Hotel Athena 5
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Hotel Athena 30
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Hotel Athena
9.0Exceptional

“Guests rave about Hotel Athena's exceptional staff and prime location near Siena, praising its convenient parking, stunning Tuscan views from the terrace, delicious breakfasts, and ideal position for exploring Chiara wine country and nearby towns—all at great value with complimentary amenities.”

  • Wi-Fi
  • Parking
  • Restaurant
  • Bar

Included in your trip2 Nights, P Mascagni 55

Your free time

No set plans here. Wander, linger over dinner and let Siena surprise you.

Make this trip yours

Stay longer or shorter in Florence

Your stay in FlorenceDays 5–8

3 Nights10 days total

Each night you add pushes the rest of the trip back by a day. Your dates, hotels, car and price all update for you, and you can undo it anytime.

  1. 5
    Drive day

    Florence

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    Continue to Florence for three nights. Explore the Duomo, Uffizi Gallery, Accademia and Ponte Vecchio, with time to enjoy Renaissance art, local food and evening walks along the Arno. Please reserve major museums in advance.

    Overnight: Art Atelier, night 1 of 3

Your hotel in Florence

10 hotels to choose from
Art Atelier 1
Art Atelier 2
Art Atelier 3
Art Atelier 4
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Art Atelier 6
Art Atelier 7
Art Atelier 8
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Art Atelier
9.0Exceptional

“Art Atelier is a beautifully appointed hotel in Florence's historic center, perfectly positioned within walking distance of the Duomo and main attractions on a quiet street. Guests consistently praise the excellent location, impeccable cleanliness, spacious comfortable rooms, outstanding breakfast buffet, and exceptionally helpful, professional staff who go above and beyond to enhance their stay.”

  • Breakfast available
  • Wi-Fi
  • Parking
  • Air conditioning

Included in your trip3 Nights, Via Dell'amorino 20 Red, Florence

Your free time

No set plans here. Wander, linger over dinner and let Florence surprise you.

Make this trip yours

Stay longer or shorter in Venice

Your stay in VeniceDays 8–10

2 Nights10 days total

Each night you add pushes the rest of the trip back by a day. Your dates, hotels, car and price all update for you, and you can undo it anytime.

  1. 8
    Drive day

    Venice

    Venice 1
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    Venice 4
    1 / 4

    Drive to Venice Marco Polo Airport on Day 8 and return your rental car. Continue by pre-arranged boat transfer to your Venice hotel. Explore Saint Mark’s Square, the Doge’s Palace and the city’s canals, with an optional excursion to Murano and Burano. On Day 10, take the included boat transfer from your hotel area back to Venice Marco Polo Airport for departure.

    Overnight: B&b Hotel Venezia Laguna, night 1 of 2

Your hotel in Venice

10 hotels to choose from
B&b Hotel Venezia Laguna 1
1 / 1
B&b Hotel Venezia Laguna
9.2Exceptional

“B&B Hotel Venezia Laguna impresses guests with its brand-new, modern facilities, spotless rooms, and excellent location near Venice's ferry and train connections. Visitors rave about the attentive staff, delicious buffet breakfasts, and comfortable amenities, making it an ideal base for exploring Venice.”

Included in your trip2 Nights, Isola Nova Del Tronchetto, Venice

Your free time

No set plans here. Wander, linger over dinner and let Venice surprise you.

Your car

A rental car is included for all 10 days. Want more room or comfort? Upgrade below.

Pick up, day 1FIUMICINO (FCO)

Return, day 10TESSERA-VENICE (VCE)

Good to knowRates assume a driver aged 30 or over.

What's in the price

Included

  • 9 nights’ accommodation in selected hotels
  • One-way rental car from Rome Fiumicino Airport to Venice Marco Polo Airport, as selected
  • Round-trip boat transfers between Venice Marco Polo Airport and the Venice hotel
  • Detailed self-drive itinerary and route guidance

Not included

  • International and domestic flights
  • Fuel, road tolls, parking charges, traffic fines and restricted-zone penalties
  • Meals, drinks and sightseeing unless specifically stated
  • Optional excursions, gondola rides and guided tours
  • Local city taxes payable directly at the hotels
  • Personal expenses and gratuities

Operated by Avia Travel & Tours.

Want to read it later?

Download this tour's PDF brochure and plan offline: every day, your hotels, the car and our phone numbers.

Questions travelers ask

Want to change something?

Our travel experts know these roads. Call and we'll tailor the trip with you.

Call +1 858 275 8851
Estimated trip price

US$1,988per person

US$3,976total for 2 travelers

  • Includes: 9 hotel nights + 9-day rental car
  • Based on 2 travelers sharing 1 room and 1 car
  • Flight priced separately once you pick one

Would you like to add round-trip flights from your home airport, into Rome and home from Venice?

Travel date

Travelers

Live hotel, car & flight prices on the next step.

TPEarn up to 7,500 TPoints (worth $75) on this booking, redeem for flights, hotels, cars and more. Free to join; sign in to start collecting.

Plan your adventure:Talk to a travel expert

Estimated total, 2 travelersUS$3,976

Still deciding? Compare similar tours

How this road trip stacks up against similar self-drive tours, side by side.

Tour
This tour
Fly-Drive Rome to Venice10 days, 9 nights
Croatia Fly-Drive Highlights10 days, 9 nights
Slow Scenic Albania Fly & Drive9 days, 8 nights
Fly-Drive Alpine Highlights Loop9 days, 8 nights
Price, per person
FromUS$1,988US$240US$420US$712
Per nightUS$221 / nightUS$27 / nightBestUS$53 / nightUS$89 / night
The trip
Duration10 days, 9 nights10 days, 9 nights9 days, 8 nights9 days, 8 nights
Stops4547
PlacesRome, Siena, Florence, VeniceZagreb, Plitvice Entrance 1 Ticket Office, Zadar, SplitTirana, Gjirokaster, Himarë, BeratMunich, Garmisch-Partenkirchen, Merano, Davos, Fuessen, Augsburg
Start and finishRome – VeniceZagrebTiranaMunich
On the road
Total drivingAbout 550 kmAbout 720 kmAbout 300 kmAbout 620 km
Longest drive dayAbout 255 kmAbout 325 kmAbout 175 kmAbout 135 kmBest
Car includedCompactYesCompactCompact
Stays and extras
Hotels included3 to 4-star hotels3 to 4-star hotels2 to 3-star hotels2 to 4-star hotels
Hotel choiceAbout 10 hotels per stopBestAbout 10 hotels per stopAbout 10 hotels per stopAbout 9 hotels per stop
Airport transferNot includedNot includedNot includedNot included
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"From" prices are per person for 2 travelers sharing, at the cheapest hotels. Driving is estimated from the stop locations.

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